Medicine Workspace · Established evidence
Understand the medicine before the next access discussion.
Bring the medicine's regulatory history, HTA position, clinical and safety evidence, and economics into one connected review. Explore the conclusions first, then examine the populations, comparators and sources behind them.
Prepare for payer discussions, assess competing evidence and identify the questions that still need resolving.
Prepare the next payer discussion
Start with the medicine's established position, then examine the evidence relevant to the discussion ahead. Review regulatory history, agency assessments, clinical and safety findings, and economics without treating them as interchangeable conclusions.
Examine the scope behind each finding
Check the population, comparator and conditions of use before carrying a finding into an access argument. Formulation and route stay distinct, and combination medicines are reviewed separately from their individual ingredients.

Follow the next question
Use HTA Library to investigate appraisal reasoning, Evidence Finder to locate supporting evidence or Executive Briefs to prepare a report for colleagues. Scenario estimates stay separate from established findings, and each finding remains limited to the medicine, indication, population and source in which it was reported.
Sources behind these findings
as recorded
TA393: 14 verified trial endpoint results
Source: Synapptiq TA393 evidence review; Synapptiq application · Reviewed 2026-10-27 · Review due 2027-10-27
as recorded
TA393 model: Markov, 1-year cycle, 3.5% discount
Source: Synapptiq TA393 evidence review; Synapptiq application · Reviewed 2026-10-27 · Review due 2027-10-27
Continue your evidence review
Decision focus: Review medicine evidence and access
What does the published evidence support for this medicine?
For Market access and HEORConnected capabilities
Worked example
Alirocumab: examining NICE TA3931 of 9 capabilities
