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Medicine Workspace · Established evidence

Understand the medicine before the next access discussion.

Bring the medicine's regulatory history, HTA position, clinical and safety evidence, and economics into one connected review. Explore the conclusions first, then examine the populations, comparators and sources behind them.

Prepare for payer discussions, assess competing evidence and identify the questions that still need resolving.

Prepare the next payer discussion

Start with the medicine's established position, then examine the evidence relevant to the discussion ahead. Review regulatory history, agency assessments, clinical and safety findings, and economics without treating them as interchangeable conclusions.

Examine the scope behind each finding

Check the population, comparator and conditions of use before carrying a finding into an access argument. Formulation and route stay distinct, and combination medicines are reviewed separately from their individual ingredients.

Editorial artwork: a medicine vial on dark stone, connected by fine threads of light to its evidence papers

Follow the next question

Use HTA Library to investigate appraisal reasoning, Evidence Finder to locate supporting evidence or Executive Briefs to prepare a report for colleagues. Scenario estimates stay separate from established findings, and each finding remains limited to the medicine, indication, population and source in which it was reported.

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Sources behind these findings

  • as recorded

    TA393: 14 verified trial endpoint results

    Source: Synapptiq TA393 evidence review; Synapptiq application · Reviewed 2026-10-27 · Review due 2027-10-27

  • as recorded

    TA393 model: Markov, 1-year cycle, 3.5% discount

    Source: Synapptiq TA393 evidence review; Synapptiq application · Reviewed 2026-10-27 · Review due 2027-10-27

Continue your evidence review

Decision focus: Review medicine evidence and access

What does the published evidence support for this medicine?

For Market access and HEOR

Connected capabilities

1 of 9 capabilities